Driving Directions to Macomb Western Illinois University's residential campus is located in Macomb, Illinois, at the hub of Highways 67 (north-south) and 136 (east-west).
- From the Chicago area: travel west on I-88 or I-80. On I-88W, take exit #1A to I-74 east to Peoria. On I-80W, exit I-74 east to Peoria. On I-74 east, take exit #46A to U.S. 34 west to Galesburg/Monmouth. At Monmouth, travel Highway 67 south, 30 miles to Macomb. (Note: Amtrak provides swift, affordable rail service from Chicago to Macomb with nine stops en route.) For more information see Travel Directions to Macomb or visit "Amtrak.com"
- From St. Louis and other points south: Travel on U.S. 67 north to Macomb through Illinois; OR travel on I-70 west or U.S. 40/61 north to U.S. 61 north. At Hannibal, travel on U.S. 36 east to I-172/U.S. 336/IL 94 north. At Carthage, travel U.S. 136 east 25 miles to Macomb.
- From Eastern Illinois: Find the most convenient route to Highway 136 and travel west to Macomb.
- Other Locations: [check "Google Maps"]