Mass Spectrometry Center

Instrumentation

The Western Illinois Mass Spec Center is equipped with an Agilent 6545 Q-TOF LC/MS system with the following modules: a 6545 quadrupole time-of-flight (Q-TOF) mass spectrometer, a 1260 Infinity II binary liquid chromatography (LC) system, a 7890B gas chromatography (GC) system, and three atmospheric pressure ionization (API) sources including a Dual Agilent Jet Stream (AJS) electrospray ionization (ESI) source, an atmospheric pressure chemical ionization (APCI) source, and a GC-APCI interface. The system is able to do the following analysis: LC-DAD, LC-ESI/MS(/MS), LC-APCI/MS(/MS), and GC-APCI/MS(/MS).

Agilent 6545 Q-TOF Mass Spectrometer

The Agilent 6545 Q-TOF mass spectrometer is a state-of-the-art quadrupole time-of-flight mass spectrometer that performs both high resolution mass spectrometry (HRMS) and high-resolution tandem mass spectrometry (HRMS/MS). It consists of a quadrupole mass analyzer, a hexapole collision cell, and a high resolution time-of-flight mass analyzer. 

Agilent 1260 Infinity II Binary LC System

The Agilent 1260 Infinity II Binary LC System consists of an Agilent 1260 Infinity II Binary Pump with an integrated vacuum degasser, an Agilent 1260 Infinity II Vialsampler, an Agilent 1260 Infinity II Multicolumn Thermostat (MCT), and an Agilent 1290 Infinity II Diode Array Detector (DAD).

Agilent 7890B GC System

The Agilent 7890B GC System is a state-of-the-art gas chromatograph. Key to its performance is the use of advanced electronic pneumatic control (EPC) modules and high-performance GC oven temperature control.

Atmospheric pressure ionization (API) sources

The Agilent 6545 Q-TOF mass spectrometer at the Western Illinois Mass Spec Center is equipped with the following interchangeable API sources: Dual Agilent Jet Stream (AJS) electrospray ionization (ESI) source, atmospheric pressure chemical ionization (APCI) source, and GC-APCI interface. A common atmospheric sampling interface introduces ions from these various sources into the vacuum system of the Agilent 6545 Q-TOF mass spectrometer.